Age and cortisol suppression by dexamethasone in normal subjects.

  title={Age and cortisol suppression by dexamethasone in normal subjects.},
  author={Myron Frederick Weiner},
  journal={Journal of psychiatric research},
  volume={23 2},
A study of 60 healthy volunteers ranging from 19-88 yr of age found nonsuppression rare (5%) and confirmed that the dexamethasone suppression test (DST) of the reactivity of the hypophyseal-pituitary-adrenal axis to negative feedback inhibition requires 0800 h plasma dexamethasone (DEX) levels in excess of 220 ng/dl. All of the subjects with inadequate DEX levels (N = 3) were older than 50 yr of age as were the nonsuppressors (N = 3); two of the three nonsuppressors had inadequate DEX… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-6 of 6 extracted citations

Similar Papers

Loading similar papers…