• Biology
  • Published 2013

Age- and Experience-Related Distribution of Parvalbumin-Expressing GABAergic Interneurons within the Hippocampus & Surrounding Cortices

@inproceedings{Corriveau2013AgeAE,
  title={Age- and Experience-Related Distribution of Parvalbumin-Expressing GABAergic Interneurons within the Hippocampus & Surrounding Cortices},
  author={Jennifer A. Corriveau},
  year={2013}
}
Parvalbumin (PV)-expressing inhibitory interneurons are the most numerous GABAergic interneuron type in the neocortex and hippocampus (HPC). Selective reductions in PV interneurons are observed in cortical and limbic regions in postmortem human schizophrenic brain tissue. Reductions in PV expression are also observed in rodents following acute and/or chronic treatment with NMDAantagonists (e.g. ketamine). There are inconsistencies in the literature regarding age-related changes in PV expression… CONTINUE READING

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