Age and Ageing 1996:25:470-478 Early T Cell Activation in Elderly Humans


This study characterizes the early steps of T lymphocyte activation in healthy elderly subjects. The expression of CD69, the earliest inducible antigen which appears with T lymphocyte activation, was assessed in T cells cultured with medium, anti-CD3 or PMA. The proliferative responses of T cells stimulated through CD69 and CD3 pathways were also studied… (More)


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