Age-adjustment of the D-dimer cut-off value to improve the exclusion of thromboembolic events in older patients October 2013


In 2010, Douma et al introduced a formula to adjust D-dimer cut-off values for age in outpatients >50 years: Age × 0.01 mg/L. Application of this approach in different retrospective cohorts confirmed that age adjustment increases specificity while hardly affecting sensitivity. Reducing the false positive results, the ageadjusted D-dimer cut-off point raises… (More)

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