Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: the ADJUST-PE study.

Abstract

IMPORTANCE D-dimer measurement is an important step in the diagnostic strategy of clinically suspected acute pulmonary embolism (PE), but its clinical usefulness is limited in elderly patients. OBJECTIVE To prospectively validate whether an age-adjusted D-dimer cutoff, defined as age × 10 in patients 50 years or older, is associated with an increased… (More)
DOI: 10.1001/jama.2014.2135

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@article{Righini2014AgeadjustedDC, title={Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: the ADJUST-PE study.}, author={M. Righini and Josien van Es and Paul L. den Exter and P. Roy and Franck Verschuren and Alexandre Ghuysen and Olivier Rutschmann and {\'O}. S{\'a}nchez and Morgan Jaffrelot and Albert Trinh-Duc and Catherine le Gall and Far{\`e}s Moustafa and Alessandra Principe and Anja A van Houten and Marije ten Wolde and R. Douma and Germa M Hazelaar and Petra M. G. Erkens and Klaas W. van Kralingen and Marco J J H Grootenboers and Marc F Durian and Y Whitney Cheung and Guy Meyer and Henri Bounameaux and Menno V. Huisman and Pieter Willem Kamphuisen and Gregoire Le Gal}, journal={JAMA}, year={2014}, volume={311 11}, pages={1117-24} }