Age-Specific Questionnaires Distinguish GERD Symptom Frequency and Severity in Infants and Young Children: Development and Initial Validation

@article{Deal2005AgeSpecificQD,
  title={Age-Specific Questionnaires Distinguish GERD Symptom Frequency and Severity in Infants and Young Children: Development and Initial Validation},
  author={Linda S. Deal and B. Gold and D. Gremse and H. Winter and Suzanne B Peters and P. Fraga and M. E. Mack and S. Gaylord and V. Tolia and J. Fitzgerald},
  journal={Journal of Pediatric Gastroenterology and Nutrition},
  year={2005},
  volume={41},
  pages={178-185}
}
Two gastroesophageal reflux disease (GERD) symptom questionnaires were developed and tested prospectively in a pilot study conducted in infants (1 through 11 months) and young children (1 through 4 years) with and without a clinical diagnosis of GERD. A pediatric gastroenterologist made the clinical diagnosis of GERD. Parents or guardians at 4 study sites completed the questionnaires, providing information on the frequency and severity of symptoms appropriate to the 2 age cohorts. In infants… Expand

Paper Mentions

Interventional Clinical Trial
The accumulation of fluid behind the ear drum without any acute inflammation is known as otitis media with effusion (OME). It is the most common cause of acquired hearing loss during… Expand
ConditionsOtitis Media With Effusion
InterventionDrug
Development and Psychometric Evaluation of 2 Age-stratified Versions of the Pediatric GERD Symptom and Quality of Life Questionnaire
TLDR
These results support the reliability, validity, and responsiveness of both versions of the PGSQ and should be useful for clinical studies. Expand
Frequency of Gastro-Esophageal Reflux symptoms in Healthy Children Determined by MM GERD Questionnaire in Mexico: An Exploratory Study
  • Rogelio Ramses Hernandez-Pliego, Jose Ivan Rodriguez de Molina-Serrano
  • Medicine
  • 2020
TLDR
MM GERD is a not a reliable questionnaire to explore the presence of upper gastrointestinal symptoms in healthy children from 5-17 years old and it is necessary to assess language, methodological and clinical validation of MM GERD to extrapolate these results into clinical practice. Expand
Multicenter, Randomized, Double-Blind Study Comparing 10, 20 and 40 mg Pantoprazole in Children (5-11 Years) With Symptomatic Gastroesophageal Reflux Disease
TLDR
Pantoprazole (20 and 40 mg) is effective in reducing endoscopically proven GERD symptoms in children and significantly reduced symptoms as early as 1 week. Expand
Correlation between gastroesophageal reflux disease questionnaire and erosive esophagitis in school-aged children receiving endoscopy.
TLDR
For the identification of EE in children, the Chinese GerdQ had similar sensitivity and specificity to that used for adults, and may be applied as a noninvasive screening tool. Expand
Validation issues in questionnaires for diagnosis and monitoring of gastroesophageal reflux disease in children
TLDR
Psychometric characteristics and approaches to validation of currently available pediatric GERD questionnaires are reviewed, finding advantages and disadvantages with regard to feasibility, reliability, and validity. Expand
The incidence of oropharyngeal dysphagia in infants with GERD-like symptoms.
TLDR
Oropharyngeal dysphagia is prominent in infants with GERD-like symptoms, and it is found that at-risk infants included extreme prematurity, developmental delay, or symptoms refractory to antireflux medications are identified. Expand
Prevalence and Associated Features of Gastroesophageal Reflux Symptoms in a Caucasian-Predominant Adolescent School Population
TLDR
Cigarette, alcohol, and non-steroidal anti-inflammatory drug use were risk factors for both respiratory and esophageal symptoms and fewer than 25% of students with gastroesophagal reflux symptoms consulted a physician and/or took medications. Expand
Validation issues in questionnaires for diagnosis and monitoring of gastroesophageal reflux disease in children
TLDR
Psychometric characteristics and approaches to validation of currently available pediatric GERD questionnaires are reviewed, finding advantages and disadvantages with regard to feasibility, reliability, and validity. Expand
Follow-Up After pH-Metry and pH Impedance in Pediatric Gastroesophageal Reflux Disease
TLDR
In infants, an initial high RI is associated with persistence of GI symptoms at 3 months and a higher burden of symptoms during the course of 1 year, while in children there were no such findings. Expand
Challenges in the diagnosis of gastroesophageal reflux disease in infants and children.
INTRODUCTION The diagnosis of gastroesophageal reflux disease (GERD) is challenging. The wide variation in symptoms is a major reason for the controversies. Since the expression of GERD varies fromExpand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 18 REFERENCES
Reflux Symptoms in 100 Normal Infants: Diagnostic Validity of the Infant Gastroesophageal Reflux Questionnaire
TLDR
It is found that normal infants had a high prevalence of reflux symptoms, such as daily regurgitation, respiratory symptoms, crying more than an hour a day, arching, or daily hiccups but that many symptoms were significantly more prevalent in the GERD than in the normal infants. Expand
Symptoms associated with gastroesophageal reflux disease: development of a questionnaire for use in clinical trials.
TLDR
Comparison of effect sizes showed the GSAS is sensitive to changes in severity of symptoms and is a reliable, valid, and responsive measure of GERD symptoms. Expand
Reliability and Validity of an Infant Gastroesophageal Reflux Questionnaire
TLDR
An Infant Gastroesophageal Reflux Questionnaire consisting of 161 items covering demographics, symptoms and possible causes can aid pediatricians in making decisions regarding diagnoses and treatment in this common but complex disorder. Expand
Prevalence of symptoms of gastroesophageal reflux during infancy. A pediatric practice-based survey. Pediatric Practice Research Group.
TLDR
Complaints of regurgitation are common during the first year of life, peaking at 4 months of age, and many infants "outgrow" overt GER by 7 months and most by 1 year. Expand
Prevalence of symptoms of gastroesophageal reflux during childhood: a pediatric practice-based survey. Pediatric Practice Research Group.
TLDR
Symptoms suggestive of GER are not rare in childhood, yet only a fraction of children with symptoms are treated with over-the-counter antacids or histamine2 antagonists, and Prospective longitudinal data are needed to determine which children with Symptoms of GER actually have GER disease and are at risk of developing complications. Expand
One-year follow-up of symptoms of gastroesophageal reflux during infancy. Pediatric Practice Research Group.
TLDR
Infants with daily or problematic regurgitation at 6 to 12 months of age outgrew this within the following year and there was no increase in respiratory illnesses in infants with a history of Regurgitation. Expand
One-Year Follow-up of Symptoms of Gastroesophageal Reflux During Infancy
TLDR
Infants with daily or problematic regurgitation at 6 to 12 months of age outgrew this within the following year and there was no increase in respiratory illnesses in infants with a history of regurgitations. Expand
Epidemiology and management of gastro‐oesophageal reflux in children
  • B. Gold
  • Medicine
  • Alimentary pharmacology & therapeutics
  • 2004
TLDR
Paediatric gastro‐oesophageal reflux (GER) is likely to share a similar pathophysiology to adult GER, and mounting evidence from published preliminary data suggests a genetic susceptibility to GERD, but further studies will be necessary to confirm this hypothesis. Expand
Outcomes of Pediatric Gastroesophageal Reflux Disease: In the First Year of Life, in Childhood, and in Adults . . . Oh, and Should We Really Leave Helicobacter pylori Alone?
  • B. Gold
  • Medicine
  • Journal of pediatric gastroenterology and nutrition
  • 2003
TLDR
To better understand pediatric GERD, age-appropriate case definitions and multicenter randomized controlled treatment trials are critically needed. Expand
Tests to Assess Symptoms of Gastroesophageal Reflux in Infants and Children
  • S. Orenstein
  • Medicine
  • Journal of pediatric gastroenterology and nutrition
  • 2003
In studying antireflux medications, we may use tests for assessing symptoms of gastroesophageal reflux to establish or confirm a diagnosis of reflux disease and to evaluate whether study subjects areExpand
...
1
2
...