Age-Specific Effects of Voluntary Exercise on Memory and the Older Brain

@article{Siette2013AgeSpecificEO,
  title={Age-Specific Effects of Voluntary Exercise on Memory and the Older Brain},
  author={Joyce Siette and Reginald Frederick Westbrook and Carl Cotman and Kuldip Singh Sidhu and Michael J. Valenzuela},
  journal={Biological Psychiatry},
  year={2013},
  volume={73},
  pages={435-442}
}
BACKGROUND Physical exercise in early adulthood and mid-life improves cognitive function and enhances brain plasticity, but the effects of commencing exercise in late adulthood are not well-understood. METHOD We investigated the effects of voluntary exercise in the restoration of place recognition memory in aged rats and examined hippocampal changes of synaptic density and neurogenesis. RESULTS We found a highly selective age-related deficit in place recognition memory that is stable across… CONTINUE READING
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