Age-Related Changes in Sirtuin 7 Expression in Calorie-Restricted and Refed Rats Agata

Abstract

Background: Sirtuins (SIRT1–7) have been implicated to mediate the beneficial effects of calorie restriction for healthy aging. While the physiological functions of SIRT7 are still poorly understood, SIRT7 has recently been shown to affect ribosome biogenesis, mitochondrial gene expression, and hepatic lipid metabolism. Objective: To analyze the effects of… (More)

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