Age-Dependent Specific Changes in Area CA2 of the Hippocampus and Social Memory Deficit in a Mouse Model of the 22q11.2 Deletion Syndrome

@article{Piskorowski2016AgeDependentSC,
  title={Age-Dependent Specific Changes in Area CA2 of the Hippocampus and Social Memory Deficit in a Mouse Model of the 22q11.2 Deletion Syndrome},
  author={Rebecca Ann Piskorowski and Kaoutsar Nasrallah and Anastasia Diamantopoulou and Jun Mukai and Sami I. H. Hassan and Steven A. Siegelbaum and Joseph A Gogos and Vivien Chevaleyre},
  journal={Neuron},
  year={2016},
  volume={89},
  pages={163-176}
}
Several neuropsychiatric disorders are associated with cognitive and social dysfunction. Postmortem studies of patients with schizophrenia have revealed specific changes in area CA2, a long-overlooked region of the hippocampus recently found to be critical for social memory formation. To examine how area CA2 is altered in psychiatric illness, we used the Df… CONTINUE READING