Age-Dependent Changes in the Proteome Following Complete Spinal Cord Transection in a Postnatal South American Opossum (Monodelphis domestica)

@inproceedings{Noor2011AgeDependentCI,
  title={Age-Dependent Changes in the Proteome Following Complete Spinal Cord Transection in a Postnatal South American Opossum (Monodelphis domestica)},
  author={Natassya M. Noor and David L. Steer and Benjamin J. Wheaton and Carl Joakim Ek and Jessie S. Truettner and W. Dalton Dietrich and Katarzyna Magdalena Dziegielewska and Samantha J. Richardson and Alexander Ian Smith and John L Vandeberg and Norman R Saunders},
  booktitle={PloS one},
  year={2011}
}
Recovery from severe spinal injury in adults is limited, compared to immature animals who demonstrate some capacity for repair. Using laboratory opossums (Monodelphis domestica), the aim was to compare proteomic responses to injury at two ages: one when there is axonal growth across the lesion and substantial behavioural recovery and one when no axonal growth occurs. Anaesthetized pups at postnatal day (P) 7 or P28 were subjected to complete transection of the spinal cord at thoracic level T10… CONTINUE READING
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