Age-Associated Increase in BMP Signaling Inhibits Hippocampal Neurogenesis.

Abstract

Hippocampal neurogenesis, the product of resident neural stem cell proliferation and differentiation, persists into adulthood but decreases with organismal aging, which may contribute to the age-related decline in cognitive function. The mechanisms that underlie this decrease in neurogenesis are not well understood, although evidence in general indicates… (More)
DOI: 10.1002/stem.1943

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