Age, sex, and gonadal hormones differently influence anxiety- and depression-related behavior during puberty in mice.

@article{Boivin2017AgeSA,
  title={Age, sex, and gonadal hormones differently influence anxiety- and depression-related behavior during puberty in mice.},
  author={Josiah R. Boivin and David John Piekarski and Jessica K Wahlberg and Linda Wilbrecht},
  journal={Psychoneuroendocrinology},
  year={2017},
  volume={85},
  pages={
          78-87
        }
}
Anxiety and depression symptoms increase dramatically during adolescence, with girls showing a steeper increase than boys after puberty onset. The timing of the onset of this sex bias led us to hypothesize that ovarian hormones contribute to depression and anxiety during puberty. In humans, it is difficult to disentangle direct effects of gonadal hormones… CONTINUE READING