Agarwood Induced Laxative Effects via Acetylcholine Receptors on Loperamide-Induced Constipation in Mice

@article{Kakino2010AgarwoodIL,
  title={Agarwood Induced Laxative Effects via Acetylcholine Receptors on Loperamide-Induced Constipation in Mice},
  author={Mamoru Kakino and H. Izuta and T. Ito and K. Tsuruma and Y. Araki and M. Shimazawa and M. Oyama and Munekazu Iinuma and H. Hara},
  journal={Bioscience, Biotechnology, and Biochemistry},
  year={2010},
  volume={74},
  pages={1550 - 1555}
}
  • Mamoru Kakino, H. Izuta, +6 authors H. Hara
  • Published 2010
  • Chemistry, Medicine
  • Bioscience, Biotechnology, and Biochemistry
  • Agarwood (Aquilaria sinensis, Aquilaria crasna) is well known as an incense in the oriental region such as Thailand, Taiwan, and Cambodia, and is used as a digestive in traditional medicine. We investigated the laxative effects and mechanism of agarwood leaves extracted with ethanol (EEA-1, Aquilaria sinensis; EEA-2, Aquilaria crasna). EEA-1, EEA-2, the main constituents of EEAs (mangiferin, and genkwanin-5-O-primeveroside), and senna increased the frequency and weight of stools in loperamide… CONTINUE READING
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