• DOI:10.1271/bbb.100122
Corpus ID: 3047349

Agarwood Induced Laxative Effects via Acetylcholine Receptors on Loperamide-Induced Constipation in Mice

@article{Kakino2010AgarwoodIL,
  title={Agarwood Induced Laxative Effects via Acetylcholine Receptors on Loperamide-Induced Constipation in Mice},
  author={Mamoru Kakino and H. Izuta and T. Ito and K. Tsuruma and Y. Araki and M. Shimazawa and M. Oyama and Munekazu Iinuma and H. Hara},
  journal={Bioscience, Biotechnology, and Biochemistry},
  year={2010},
  volume={74},
  pages={1550 - 1555}
}

Mamoru Kakino, H. Izuta, +6 authors H. Hara

Published 2010

Chemistry, Medicine

Bioscience, Biotechnology, and Biochemistry

Agarwood (Aquilaria sinensis, Aquilaria crasna) is well known as an incense in the oriental region such as Thailand, Taiwan, and Cambodia, and is used as a digestive in traditional medicine. We investigated the laxative effects and mechanism of agarwood leaves extracted with ethanol (EEA-1, Aquilaria sinensis; EEA-2, Aquilaria crasna). EEA-1, EEA-2, the main constituents of EEAs (mangiferin, and genkwanin-5-O-primeveroside), and senna increased the frequency and weight of stools in loperamide… CONTINUE READING

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