AgRP and POMC neurons are hypophysiotropic and coordinately regulate multiple endocrine axes in a larval teleost.

@article{Zhang2012AgRPAP,
  title={AgRP and POMC neurons are hypophysiotropic and coordinately regulate multiple endocrine axes in a larval teleost.},
  author={Chao Zhang and Paul M. Forlano and Roger D Cone},
  journal={Cell metabolism},
  year={2012},
  volume={15 2},
  pages={256-64}
}
Plasticity in growth and reproductive behavior is found in many vertebrate species, but is common in male teleost fish. Typically, "bourgeois" males are considerably larger and defend breeding territories while "parasitic" variants are small and use opportunistic breeding strategies. The P locus mediates this phenotypic variation in Xiphophorus and encodes variant alleles of the melanocortin-4 receptor (MC4R). However, deletion of the MC4R has modest effects on somatic growth and reproduction… CONTINUE READING
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Themelanocortin-4 receptor: physiology, pharmacology, and pathophysiology

  • Y. X. Tao
  • Endocr. Rev
  • 2010
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