AgOTf-catalyzed three-component reactions of 2-alkynylbenzaldehydes, amines, and diethylphosphite. An efficient route to 2,3-disubstituted-1,2-dihydroisoquinolin-1-ylphosphonates.

@article{Sun2007AgOTfcatalyzedTR,
  title={AgOTf-catalyzed three-component reactions of 2-alkynylbenzaldehydes, amines, and diethylphosphite. An efficient route to 2,3-disubstituted-1,2-dihydroisoquinolin-1-ylphosphonates.},
  author={Wei Sun and Qiuping Ding and Xiaoyu Sun and Renhua Fan and Jie Wu},
  journal={Journal of combinatorial chemistry},
  year={2007},
  volume={9 4},
  pages={690-4}
}
AgOTf was discovered as a highly efficient catalyst in reactions of 2-alkynylbenzaldehydes, amines, and diethylphosphite, which provided a facile and efficient pathway for the synthesis of 2,3-disubstituted-1,2-dihydroisoquinolin-1-ylphosphonates. 

Topic