Afterpotential characteristics and firing patterns in maturing rat hippocampal CA1 neurones in in vitro slices.

@article{Costa1991AfterpotentialCA,
  title={Afterpotential characteristics and firing patterns in maturing rat hippocampal CA1 neurones in in vitro slices.},
  author={Pedro Freire Costa and Maria Alexandra Ribeiro and Ana Isabel Santos},
  journal={Brain research. Developmental brain research},
  year={1991},
  volume={62 2},
  pages={263-72}
}
The postnatal evolution of depolarizing after-potentials (DAPs) and after-hyperpolarizations (AHPs) was studied in rat CA1 hippocampal neurones (5-68 days of age) using in vitro slices. Results were pooled into 4 age groups: P5-9, P10-16, P17-24 and P26-68. In P5-9 cells, DAPs were seen as passive signals, with a time constant similar to the time constant of the membrane. The evolution of the DAP was characterized by a decrease in amplitude, an increase in duration and a change in contour. In… CONTINUE READING

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