Aftercontractions and excitation-contraction coupling in rat cardiac muscle.

@article{Keurs1988AftercontractionsAE,
  title={Aftercontractions and excitation-contraction coupling in rat cardiac muscle.},
  author={Hendrick E D J ter Keurs and Peter Backx and Pieter P. de Tombe and Bert Mulder},
  journal={Canadian journal of physiology and pharmacology},
  year={1988},
  volume={66 9},
  pages={1239-45}
}
Calcium loading in cardiac muscle may cause spontaneous contractions (SC). We observed that SC move at a constant rate (Vsc) through isolated rat myocytes and trabeculae. Factors that influence the properties of SC were studied with Nomarsky microscopy and laser diffraction techniques. Myocytes and trabeculae were superfused with Krebs-Henseleit solution (21 degrees C, pH 7.35; Ca2+, 0.5-7 mM). Vsc in myocytes and within cells of trabeculae ranged between 50 and 150 micron/s. After a train of 3… CONTINUE READING

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