African swine fever virus encodes a CD2 homolog responsible for the adhesion of erythrocytes to infected cells.

@article{Rodrguez1993AfricanSF,
  title={African swine fever virus encodes a CD2 homolog responsible for the adhesion of erythrocytes to infected cells.},
  author={J. M{\'e}ndez Rodr{\'i}guez and R. J. Y{\'a}{\~n}ez and F. J. Adell Almaz{\'a}n and E. Vinuela and Jos{\'e} Francisco Rodr{\'i}guez},
  journal={Journal of virology},
  year={1993},
  volume={67 9},
  pages={5312-20}
}
We have identified an open reading frame, EP402R, within the EcoRI E' fragment of the African swine fever virus genome that encodes a polypeptide of 402 amino acid residues homologous to the adhesion receptor of T cells, CD2. Transcription of EP402R takes place during the late phase of virus replication. The disruption of EP402R, achieved through the replacement of a 354-bp-long fragment from within EP402R by the marker gene lacZ, does not affect the virus growth rate in vitro but abrogates the… CONTINUE READING

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