Aflatoxin biosynthesis cluster gene cypA is required for G aflatoxin formation.

  title={Aflatoxin biosynthesis cluster gene cypA is required for G aflatoxin formation.},
  author={Kenneth C. Ehrlich and P. -K. Chang and Jiujiang Yu and Peter J Cotty},
  journal={Applied and environmental microbiology},
  volume={70 11},
Aspergillus flavus isolates produce only aflatoxins B1 and B2, while Aspergillus parasiticus and Aspergillus nomius produce aflatoxins B1, B2, G1, and G2. Sequence comparison of the aflatoxin biosynthesis pathway gene cluster upstream from the polyketide synthase gene, pksA, revealed that A. flavus isolates are missing portions of genes (cypA and norB) predicted to encode, respectively, a cytochrome P450 monooxygenase and an aryl alcohol dehydrogenase. Insertional disruption of cypA in A… CONTINUE READING
Highly Influential
This paper has highly influenced 11 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
70 Extracted Citations
38 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 70 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 38 references

Similar Papers

Loading similar papers…