Aflatoxin B1: A review on metabolism, toxicity, occurrence in food, occupational exposure, and detoxification methods.

@article{Rushing2019AflatoxinBA,
  title={Aflatoxin B1: A review on metabolism, toxicity, occurrence in food, occupational exposure, and detoxification methods.},
  author={Blake R Rushing and M. Selim},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2019},
  volume={124},
  pages={
          81-100
        }
}
  • Blake R Rushing, M. Selim
  • Published 2019
  • Biology, Medicine
  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • Aflatoxins are a class of carcinogenic mycotoxins produced by Aspergillus fungi and are known to contaminate a large portion of the world's food supply. Aflatoxin B1 (AFB1) is the most potent of these compounds and has been well-characterized to lead to the development of hepatocellular carcinoma (HCC) in humans and animals. This review focuses on the metabolism of AFB1, including epoxidation and DNA adduction, as it concerns the initiation of cancer and the underlying mechanisms. The link… CONTINUE READING
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