Affinity purification and partial characterization of the zonulin/zonula occludens toxin (Zot) receptor from human brain.

Abstract

The intercellular tight junctions (TJs) of endothelial cells represent the limiting structure for the permeability of the blood-brain barrier (BBB). Although the BBB has been recognized as being the interface between the bloodstream and the brain, little is known about its regulation. Zonulin and its prokaryotic analogue, zonula occludens toxin (Zot… (More)

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