• Corpus ID: 86309098

Affinity of synthetic peptide fragments of MyoD for Id1 protein and their biological effects in several cancer cells

  title={Affinity of synthetic peptide fragments of MyoD for Id1 protein and their biological effects in several cancer cells},
  author={郭盛助 and 黃麗嬌},

Protection of the muscle stem cell state from premature differentiation

The chicken is a well-established model for amniote (including human) skeletal muscle formation because the developmental anatomy of chicken skeletal muscle matches that of mammals. The accessibility

Inhibitory effect of MyoD on the proliferation of breast cancer cells

Results indicated that MyoD inhibits the proliferation of breast cancer cells and may be a tumor suppressor factor.

The Id-protein family in developmental and cancer-associated pathways

The ability of the Id proteins to interact with structurally different proteins is likely to arise from their conformational flexibility: indeed, these proteins contain intrinsically disordered regions that undergo folding upon self- or heteroassociation.

Id proteins: emerging roles in CNS disease and targets for modifying neural stemcell behavior

Recent advances in understanding Id protein pleiotropic functions in CNS diseases are outlined and an integrated view of Id proteins and their promise as potential targets in modifying stemcell behavior to ameliorate CNS disease is proposed.

Impact of the amino acid sequence on the conformation of side chain lactam‐bridged octapeptides

The Lys‐Asp‐(i,i + 4)‐lactam bridge may succeed or fail in the stabilization of short helices, depending on the primary structure, and computational methods may be valuable tools to discriminate helix‐prone from non‐helIX‐prone peptide‐based macrolactams.

Hey Factors at the Crossroad of Tumorigenesis and Clinical Therapeutic Modulation of Hey for Anticancer Treatment

This review focuses on the involvement of Hey proteins in malignant carcinoma progression and provides valuable therapeutic information for anticancer treatment.

ID4 controls luminal lineage commitment in normal mammary epithelium and inhibits BRCA1 function in basal-like breast cancer.

This review highlights recent advances in understanding of the requirement for ID4 in mammary lineage commitment and the role forID4 in BLBC and addresses current shortfalls in this field and identifies important areas of future research.