Affinity chromatography matures as bioinformatic and combinatorial tools develop.

  title={Affinity chromatography matures as bioinformatic and combinatorial tools develop.},
  author={Yannis D. Clonis},
  journal={Journal of chromatography. A},
  volume={1101 1-2},
Affinity chromatography has the reputation of a more expensive and less robust than other types of liquid chromatography. Furthermore, the technique is considered to stand a modest chance of large-scale purification of proteinaceous pharmaceuticals. This perception is changing because of the pressure for quality protein therapeutics, and the realization that higher returns can be expected when ensuring fewer purification steps and increased product recovery. These developments necessitated a… CONTINUE READING


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