Affiliations among steroid receptors as revealed by multivariate analysis of steroid binding data

@article{Ojasoo1994AffiliationsAS,
  title={Affiliations among steroid receptors as revealed by multivariate analysis of steroid binding data},
  author={T. Ojasoo and J. Raynaud and J. Dor{\'e}},
  journal={The Journal of Steroid Biochemistry and Molecular Biology},
  year={1994},
  volume={48},
  pages={31-46}
}
  • T. Ojasoo, J. Raynaud, J. Doré
  • Published 1994
  • Biology, Medicine
  • The Journal of Steroid Biochemistry and Molecular Biology
    • To illustrate the informative value of descriptive multivariate analysis in biochemical screening, we have analyzed several data matrices relating to the binding of steroids to the estrogen, progestin, androgen, glucocorticoid and mineralocorticoid receptors in different organs and species. We first compared dendrograms of steroid hormone receptors, that were obtained by an automatic hierarchical classification analysis of the binding data, to published phylogenetic trees of nuclear receptors… CONTINUE READING
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    References

    SHOWING 1-10 OF 42 REFERENCES
    Binding of steroids to the progestin and glucocorticoid receptors analyzed by correspondence analysis.
    • 65
    Correspondence analysis applied to steroid receptor binding.
    • 47
    Unique steroid congeners for receptor studies.
    • 153
    Estrogen receptor stereochemistry: ligand binding and hormonal responsiveness
    • 37
    Evolution of the nuclear receptor gene superfamily.
    • 603
    Multivariate analysis by the minimum spanning tree method of the structural determinants of diphenylethylenes and triphenylacrylonitriles implicated in estrogen receptor binding, protein kinase C activity, and MCF7 cell proliferation.
    • 25
    Steroid flexibility and receptor specificity.
    • 60
    Relative involvement of protein kinase C and of the estrogen receptor in the cytotoxic action of a population of triphenylethylenes on MCF7 cells as revealed by correspondence factorial (CF) analysis
    • 10
    Oestriol receptor interactions: their biological importance and therapeutic implications.
    • 42
    A variant estrogen receptor messenger ribonucleic acid is associated with reduced levels of estrogen binding in human mammary tumors.
    • 112
    • PDF