Afferent Mechanisms of Pain

  title={Afferent Mechanisms of Pain},
  author={Bruce Lynn and Edward R. Perl},
Publisher Summary Most pain of peripheral origin is associated with strong stimulation, with tissue injury, or with inflammation. This chapter reviews what is known about the afferent mechanisms underlying such pain. The basic thesis is that specialized nociceptors are not only the principal, but in fact for most tissues, the sole primary afferent neurones that normally encode stimuli causing pain. This general finding does not mean that activation of nociceptors always evokes pain. The… CONTINUE READING