Aetiology of transient global amnesia

  title={Aetiology of transient global amnesia},
  author={Steven L. Lewis},
  journal={The Lancet},
  • S. Lewis
  • Published 1 August 1998
  • Medicine, Biology
  • The Lancet
Transient global amnesia may be caused by cerebral vein thrombosis.
Transient global amnesia: current perspectives
Clinical aspects, new imaging findings, and recent clinical–epidemiological data with regard to the phenotype, functional anatomy, and putative cellular mechanisms of TGA are discussed.
Title: Transient Global Amnesia
This chapter describes the principle clinical features of transient amnesic syndromes, highlighting those that help to distinguish TGA from TEA, and discusses recent advances that are beginning to unravel the aetiology of TGA.
‘Les ictus amnésiques’ and Transient Global Amnesia
Although TGA remains a clinically distinct syndrome, usually with a good prognosis, evidence of neither ischaemia nor epilepsy is demonstrable in most patients, theories of jugular venous reflux may be relevant in some but probably not in most cases of this heterogeneous disorder.
Classical diseases revisited: transient global amnesia
Transient global amnesia usually affects patients between the ages of 40 and 80 and presents classically with an abrupt onset of severe anterograde amnesia.
Transient global amnesia
A review of recent advances in the understanding of the neuropsychology, aetiology and neuroradiology of the transient global amnesia syndrome is outlined.
Transient global amnesia during transoesophageal echocardiogram
A 54-year-old woman who presented a TGA immediately after right-left shunt of saline contrast during the execution of transoesophageal echocardiography is described and aetiopathological considerations for this uncommon presentation are discussed.
Transient global amnesia heralding basilar artery thrombosis


Transient Amnesia: Clinical and Neuropsychological Aspects
This chapter discusses the Aetiology and Clinical Features of Transient Global Amnesia, and the Investigation and Management of a Patient with Transient Amnesia and the Role of the CT Scan.
Syndromes of transient amnesia: towards a classification. A study of 153 cases.
  • J. Hodges, C. Warlow
  • Medicine, Psychology
    Journal of neurology, neurosurgery, and psychiatry
  • 1990
Of 153 patients presenting with acute transient amnesia, 114 fulfilled the proposed strict diagnostic criteria for transient global amnesia (TGA), and the group of 39 patients who did not meet the criteria for TGA had a significantly worse prognosis with a high incidence of major vascular events.
A case-control study of transient global amnesia.
The similar prevalence of risk factors, but the different prognosis between TGA and TIA patients, suggest that TGA is an ischaemic event, probably not triggered by thromboembolism but by a different, possibly vasospastic, mechanism.
Transient global amnesia. Precipitating activities and other observations.
  • C. Fisher
  • Psychology
    Archives of neurology
  • 1982
Patients whose spells of transient global amnesia were triggered by special circumstances, including during highly emotional experiences, and during a dip in the cold Atlantic Ocean, suggest an electrophysiologic disturbance.
Transient global amnesia and transient ischemic attack. Natural history, vascular risk factors, and associated conditions.
The results of the case-control and longitudinal studies point to the conclusion that TGA and TIA do not share the same etiology, and it is reasoned that spreading depression may play a role in TGA.
The aetiology of transient global amnesia. A case-control study of 114 cases with prospective follow-up.
A case-control comparison of 114 transient global amnesia (TGA) patients using both normal community-based controls (n = 109) and transient ischaemic attack (TIA) controls (n = 212) showed no
An increased frequency of patent foramen ovale in patients with transient global amnesia. Analysis of 53 consecutive patients.
Investigation of the frequency of patent foramen ovale (PFO) as the prerequisite for paradoxical embolism with temporobasal ischemia in patients with transient global amnesia found that it could possibly play a role in the clinical syndrome of TGA.
Bilateral cavernous sinus thrombosis causing Korsakoff's amnesic syndrome.
It is reported that acute increases of adenosine metabolites can be detected in lumbar CSF after clinical status epilepticus in humans and are comparable with those reported by other investigators.
Transient global amnesia and dural arteriovenous fistula of the anterior cranial fossa.
From surgical experience, the excision of the vascular connection between the dura and the frontal lobe following the coagulation of the dURA mater of the anterior part of the base of the skull without extensive excision seems to be recommended.
Pathophysiology of the migraine aura. The spreading depression theory.
  • M. Lauritzen
  • Biology, Psychology
    Brain : a journal of neurology
  • 1994
The combined experimental and clinical studies point to fruitful areas in which to look for migraine treatments of the future and provide a framework within which important aspects of the migraine attack can be modelled.