Aetiology and management of hereditary aortopathy

@article{Verstraeten2017AetiologyAM,
  title={Aetiology and management of hereditary aortopathy},
  author={Aline Verstraeten and I Luyckx and Bart Loeys},
  journal={Nature Reviews Cardiology},
  year={2017},
  volume={14},
  pages={197-208}
}
Aortic aneurysms are a major health problem because they account for 1–2% of all deaths in the Western population. Although abdominal aortic aneurysms (AAAs) are more prevalent than thoracic aortic aneurysms (TAAs), TAAs have been more exhaustively studied over the past 2 decades because they have a higher heritability and affect younger individuals. Gene identification in both syndromic and nonsyndromic TAA is proceeding at a rapid pace and has already pinpointed >20 genes associated with… CONTINUE READING
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