Aetiological parallel between tonsillar and anogenital squamous-cell carcinomas

@article{Frisch1999AetiologicalPB,
  title={Aetiological parallel between tonsillar and anogenital squamous-cell carcinomas},
  author={Morten Frisch and Robert J. Biggar},
  journal={The Lancet},
  year={1999},
  volume={354},
  pages={1442-1443}
}

Studies on the occurrence and effects of human papillomavirus in tumors of the head and neck

The presence of human papillomavirus in squamous cell carcinoma of the head and neck (HNSCC) was first reported in 1985 and this association has been studied intensively and today it is known that HPV is involved in HNSCC.

Human papillomavirus and prognosis of oropharyngeal squamous cell carcinoma: implications for clinical research in head and neck cancers.

  • M. Gillison
  • Medicine
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • 2006
Patients with HPV DNA–positive oropharyngeal cancers have an approximately 60% reduction in 5-year mortality when compared with patients with HPV-negative tumors, who have a considerably worse prognosis.

Molecular epidemiology of human papillomavirus.

The causal relation between human papillomavirus and cervical cancer.

It is the right time for medical societies and public health regulators to consider the causal role of human papillomavirus infections in cervical cancer and to define its preventive and clinical implications.

Second primary head and neck tumor risk in patients with cervical cancer—SEER data analysis

The role of HPV infection in HNSCC development after a first diagnosis of cervical cancer is unknown and the need for further research is unknown.

HPV infections and tonsillar carcinoma

  • S. Syrjänen
  • Medicine, Biology
    Journal of Clinical Pathology
  • 2004
Recent data suggest a distinct pattern for HPV-16 positive TCs, a subgroup of upper aerodigestive tract tumours linked to laryngeal/oral carcinomas that have better overall and disease specific survival than HPV negative patients.

Molecular Epidemiology of Human

The recognition of papillomaviruses as a major etiologic agent for human cancers has increased their medical importance and stimulated research into developing strategies for the screening, diagnosis, prevention and treatment of HPV-associated diseases.

A Case of Tonsillar Squamous Cell Carcinoma Arising in a Married Couple

A married couple with tonsillar squamous cell carcinoma was treated, and both husband and wife had same HPV subtype (HPV-16), and local recurrence was found in the tonsil nine months after the initial treatment.

Human papillomavirus‐associated carcinomas in Hawaii and the mainland U.S.

To the authors' knowledge, human papillomavirus (HPV)‐associated carcinomas in Hawaii have not been studied in detail.

HPV infection as a carcinogenic agent in head and neck cancers

The role of human papilloma virus in cancerogenesis has been discovered in the '80s and many researches confirmed it also in HNSCC cancerogenesis, but there are quite strong evidences that in some localisations (especially tonsillar carcinoma) prognosis is generally better in HPV(+) tumors.
...

References

SHOWING 1-5 OF 5 REFERENCES

Human papillomavirus (HPV) in head and neck cancer

This study was undertaken to estimate the frequency of HPV DNA in squamous cell carcinoma (SCC) at different sites of the esophagus, head and neck and to compare the clinical behavior of HPV positive and negative tumors.

Tonsillar carcinoma in a renal graft recipient treated with cyclosporine A.

A right-sided tonsillar carcinoma is reported in a 33-year-old renal graft recipient on cyclosporine A plus low dose prednisolone treatment and the clue to the early recognition of this aggressive tumour lied in the alertness of the patient himself.

Detection of human papillomavirus DNA and oncoprotein overexpression are associated with distinct morphological patterns of tonsillar squamous cell carcinoma.

The morphology of the HPV-positive tumors suggests that HPV may have a predilection for a population of nonkeratinizing squamous cells or that the virally transformed cells inhibit keratinization of the tumor cells.

Oral cancer risk in relation to sexual history and evidence of human papillomavirus infection.

Oral SCC risk increased with self-reported decreasing age at first intercourse, increasing number of sex partners, and a history of genital warts, and HPV type 16 infection may contribute to the development of a small proportion of oral SCCs in this population.