Aerosolized terbutaline in asthmatics: development of subsensitivity with long-term administration.

@article{Weber1982AerosolizedTI,
  title={Aerosolized terbutaline in asthmatics: development of subsensitivity with long-term administration.},
  author={Robert W Weber and Julian A. Smith and H. Stanley Nelson},
  journal={The Journal of allergy and clinical immunology},
  year={1982},
  volume={70 6},
  pages={417-22}
}
The peak response and the duration of bronchodilator effect were measured after four inhalations at 20 min intervals of 250 micrograms of aerosolized terbutaline in 13 patients with bronchial asthma. Patients were initially studied after strict avoidance of all adrenergic agents for 2 wk; they were then studied at 2 wk intervals for 12 wk while receiving 500 micrograms of aerosolized terbutaline q.i.d. The initial testing (TI) and the testing at the end of 12 wk (TII) were double blind. Both… CONTINUE READING

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