Aerosolized antibiotics and ventilator-associated tracheobronchitis in the intensive care unit.

@article{Palmer2008AerosolizedAA,
  title={Aerosolized antibiotics and ventilator-associated tracheobronchitis in the intensive care unit.},
  author={Lucy Brown Palmer and Gerald C. Smaldone and John J. Chen and Daniel Baram and Tao Duan and Melinda Monteforte and Marie L Varela and Ann K Tempone and Tomas O'riordan and Feroza Daroowalla and Paul S Richman},
  journal={Critical care medicine},
  year={2008},
  volume={36 7},
  pages={
          2008-13
        }
}
CONTEXT In critically ill intubated patients, signs of respiratory infection often persist despite treatment with potent systemic antibiotics. OBJECTIVE The purpose of this study was to determine whether aerosolized antibiotics, which achieve high drug concentrations in the target organ, would more effectively treat respiratory infection and decrease the need for systemic antibiotics. DESIGN Double-blind, randomized, placebo-controlled study performed from 2003 through 2004. SETTING The… CONTINUE READING

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