Aerosol therapy and the fighting toddler: is administration during sleep an alternative?

@article{Janssens2003AerosolTA,
  title={Aerosol therapy and the fighting toddler: is administration during sleep an alternative?},
  author={Hettie M. Janssens and Els C W van der Wiel and Anton F. M. Verbraak and Johan C. de Jongste and Peter J F M Merkus and Harm A. W. M. Tiddens},
  journal={Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine},
  year={2003},
  volume={16 4},
  pages={395-400}
}
Insufficient cooperation during administration of aerosols by pressurized metered dose inhaler (pMDI)/spacers is a problem in nearly 50% of treated children younger than 2 years. For these children, administration during sleep might be more efficient. However, it is unknown how much aerosol reaches the lungs during sleep. The aim of this study was to determine in vitro the lung dose in young children from a pMDI/spacer during sleep and while being awake. Breathing patterns were recorded by a… CONTINUE READING

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