Aerosol deposition in the human lung in reduced gravity.

  title={Aerosol deposition in the human lung in reduced gravity.},
  author={Chantal Darquenne},
  journal={Journal of aerosol medicine and pulmonary drug delivery},
  volume={27 3},
The deposition of aerosol in the human lung occurs mainly through a combination of inertial impaction, gravitational sedimentation, and diffusion. For 0.5- to 5-μm-diameter particles and resting breathing conditions, the primary mechanism of deposition in the intrathoracic airways is sedimentation, and therefore the fate of these particles is markedly affected by gravity. Studies of aerosol deposition in altered gravity have mostly been performed in humans during parabolic flights in both… CONTINUE READING