Aerosol deposition in health and disease.

  title={Aerosol deposition in health and disease.},
  author={Chantal Darquenne},
  journal={Journal of aerosol medicine and pulmonary drug delivery},
  volume={25 3},
The success of inhalation therapy is not only dependent upon the pharmacology of the drugs being inhaled but also upon the site and extent of deposition in the respiratory tract. This article reviews the main mechanisms affecting the transport and deposition of inhaled aerosol in the human lung. Aerosol deposition in both the healthy and diseased lung is described mainly based on the results of human studies using nonimaging techniques. This is followed by a discussion of the effect of flow… CONTINUE READING
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