Aerosol delivery to ventilated newborn infants: historical challenges and new directions

@inproceedings{Mazela2010AerosolDT,
  title={Aerosol delivery to ventilated newborn infants: historical challenges and new directions},
  author={Jan L Mazela and Richard A. Polin},
  booktitle={European Journal of Pediatrics},
  year={2010}
}
There are several aerosolized drugs which have been used in the treatment of neonatal respiratory illnesses, such as bronchodilators, diuretics, and surfactants. Preclinical in vitro and in vivo studies identified a number of variables that affect aerosol efficiency, including particle size, aerosol flows, nebulizer choice, and placement. Nevertheless, an optimized aerosol drug delivery system for mechanically ventilated infants still does not exist. Increasing interest in this form of drug… CONTINUE READING

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Respiratory Care for the Ventilated Neonate

Canadian respiratory journal • 2018
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