Aerobic training and angiogenesis activation in patients with stable chronic heart failure: a preliminary report.

@article{Eleuteri2013AerobicTA,
  title={Aerobic training and angiogenesis activation in patients with stable chronic heart failure: a preliminary report.},
  author={Ermanno Eleuteri and Alessandro Mezzani and Antonino Di Stefano and Davide Vallese and Isabella Gnemmi and Lorena Delle Donne and Adriano Taddeo and Silvia Della Bella and Pantaleo Giannuzzi},
  journal={Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals},
  year={2013},
  volume={18 5},
  pages={
          418-24
        }
}
The pathophysiology of chronic heart failure (CHF) involves multiple hystologic and molecular alterations. To determine the effects of physical training on circulating endothelial progenitor cells (EPCs), angiogenesis (angiogenin, angiopoietin-1 and -2, VEGF, Tie-2, SDF-1α) and inflammation (IL-6, CRP), we compared data obtained from 11 CHF pts before and after 3 months aerobic exercise training, to those from 10 non trained CHF pts (CHF-C group, age 64 + 2 years, NYHA 2). At the end of the… CONTINUE READING
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