Aerobic Exercise and Pharmacological Therapies for Skeletal Myopathy in Heart Failure: Similarities and Differences

@inproceedings{Bacurau2016AerobicEA,
  title={Aerobic Exercise and Pharmacological Therapies for Skeletal Myopathy in Heart Failure: Similarities and Differences},
  author={Aline Villa Nova Bacurau and Telma F{\'a}tima da Cunha and Rodrigo Alves de Souza and Vanessa Azevedo Voltarelli and Daniele Gabriel-Costa and Patr{\'i}cia C Brum},
  booktitle={Oxidative medicine and cellular longevity},
  year={2016}
}
Skeletal myopathy has been identified as a major comorbidity of heart failure (HF) affecting up to 20% of ambulatory patients leading to shortness of breath, early fatigue, and exercise intolerance. Neurohumoral blockade, through the inhibition of renin angiotensin aldosterone system (RAS) and β-adrenergic receptor blockade (β-blockers), is a mandatory pharmacological therapy of HF since it reduces symptoms, mortality, and sudden death. However, the effect of these drugs on skeletal myopathy… CONTINUE READING
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