Advocating the Development of Next-Generation High-Relaxivity Gadolinium Chelates for Clinical Magnetic Resonance.

@article{Runge2018AdvocatingTD,
  title={Advocating the Development of Next-Generation High-Relaxivity Gadolinium Chelates for Clinical Magnetic Resonance.},
  author={Val M. Runge and Johannes T. Heverhagen},
  journal={Investigative radiology},
  year={2018},
  volume={53 7},
  pages={
          381-389
        }
}
The question of improved relaxivity, and potential efficacy therein, for a next-generation of magnetic resonance gadolinium chelates with extracellular distribution and renal excretion, which could also be viewed from the perspective of dose, is addressed on the basis of historical development, animal experimentation, and human trials. There was no… CONTINUE READING