Adverse reactions to thalidomide in patients infected with human immunodeficiency virus.

@article{Haslett1997AdverseRT,
  title={Adverse reactions to thalidomide in patients infected with human immunodeficiency virus.},
  author={Patrick A. J. Haslett and J Tramontana and Margaret Burroughs and Mark Hempstead and Gilla Kaplan},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={1997},
  volume={24 6},
  pages={1223-7}
}
Thalidomide is emerging as a useful agent in the management of several complications of disease due to human immunodeficiency virus (HIV). We conducted three prospective studies of 56 HIV-infected patients who were treated with thalidomide for 14-21 days; 24 (43%) of these patients discontinued therapy owing to adverse reactions. Cutaneous and/or febrile reactions were the most frequent toxicities, arising in 20 (36%) of the patients. These reactions occurred after a mean interval (+/-SD) of 10… CONTINUE READING

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