Adverse reactions to antidepressants.

@article{Uher2009AdverseRT,
  title={Adverse reactions to antidepressants.},
  author={Rudolf Uher and Anne Farmer and Neven Henigsberg and Marcella Rietschel and Ole Mors and Wolfgang Maier and Dejan Kozel and Joanna Hauser and Daniel Souery and Anna Placentino and Jana Strohmaier and Nader Perroud and Astrid W. Zobel and Aleksandra Rajewska-Rager and M Z Dernovsek and Erik Roj Larsen and Petra Kalember and Caterina Giovannini and Mara Barreto and Peter McGuffin and Katherine J. Aitchison},
  journal={The British journal of psychiatry : the journal of mental science},
  year={2009},
  volume={195 3},
  pages={
          202-10
        }
}
  • R. Uher, A. Farmer, +18 authors K. Aitchison
  • Published 1 September 2009
  • Psychology, Medicine
  • The British journal of psychiatry : the journal of mental science
BACKGROUND Adverse drug reactions are important determinants of non-adherence to antidepressant treatment, but their assessment is complicated by overlap with depressive symptoms and lack of reliable self-report measures. AIMS To evaluate a simple self-report measure and describe adverse reactions to antidepressants in a large sample. METHOD The newly developed self-report Antidepressant Side-Effect Checklist and the psychiatrist-rated UKU Side Effect Rating Scale were repeatedly… 
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199 Citations
Highly Influential Citations
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Background Citations
61
Methods Citations
29
Results Citations
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199 Citations

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A cost-benefit analysis that cannot justify the extremely high prescription rates for these drugs is implied, especially in the emotional, psychological and interpersonal domains.
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Escitalopram treatment was efficacious and well tolerated in patients with first episode of MDD and nearly two third patients achieved remission at the end of eight week.
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