Adverse reactions among patients being treated for MDR-TB in Tomsk, Russia.

@article{Shin2007AdverseRA,
  title={Adverse reactions among patients being treated for MDR-TB in Tomsk, Russia.},
  author={Sonya S. Shin and Alexander D Pasechnikov and Irina Y Gelmanova and Gennadiy G Peremitin and Aivar K. Strelis and Sergey P. Mishustin and Alexander Barnashov and Y Karpeichik and Yevgeny G Andreev and Vera T Golubchikova and Tamara P Tonkel and Galina V Yanova and Askar B Yedilbayev and Michael L Rich and Joia S. Mukherjee and Jennifer Furin and Sidney A Atwood and Paul Farmer and Salmaan A Keshavjee},
  journal={The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease},
  year={2007},
  volume={11 12},
  pages={1314-20}
}
BACKGROUND AND SIGNIFICANCE Treatment of multidrug-resistant tuberculosis (MDR-TB) is challenging because of the toxicity of second-line medications. Little is known about whether adverse events impact treatment outcome. METHODS We conducted a retrospective case series of 244 MDR-TB patients enrolled in Tomsk between 10 September 2000 and 10 September 2002. Adverse reactions were determined by laboratory data and/or clinical criteria. A multiple logistic regression model was performed to… CONTINUE READING
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