Adverse events occurring after smallpox vaccination.

  title={Adverse events occurring after smallpox vaccination.},
  author={John Michael Lane and Joel W. Goldstein},
  journal={Seminars in pediatric infectious diseases},
  volume={14 3},
We reviewed the literature on adverse events reported to occur after smallpox vaccination. Nearly one-half of the United States population is vaccinia-naïve and may be at risk for development of serious adverse events. We describe the clinical features of postvaccinial central nervous system disease, progressive vaccinia, eczema vaccinatum, accidental implantations, "generalized vaccinia," and the common erythematous and/or urticarial rashes. In the 1960s, death occurred approximately once in… CONTINUE READING