Adverse events associated with testosterone replacement in middle-aged and older men: a meta-analysis of randomized, placebo-controlled trials.

@article{Calof2005AdverseEA,
  title={Adverse events associated with testosterone replacement in middle-aged and older men: a meta-analysis of randomized, placebo-controlled trials.},
  author={O. M. Calof and Atam B. Singh and Martin L. Lee and A. Kenny and R. Urban and J. Tenover and S. Bhasin},
  journal={The journals of gerontology. Series A, Biological sciences and medical sciences},
  year={2005},
  volume={60 11},
  pages={
          1451-7
        }
}
BACKGROUND We performed a meta-analysis of randomized clinical trials to determine the risks of adverse events associated with testosterone replacement in older men. METHODS The MEDLINE database was searched from 1966 to April 2004, using testosterone as the indexing term; limits included human, male, > or =45 years old, and randomized controlled trial. Of the 417 studies thus identified, 19 met the inclusion criteria: testosterone replacement for at least 90 days, men > or =45 years old with… Expand
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