Adverse event profile of tramadol in recent clinical studies of chronic osteoarthritis pain

@article{Langley2010AdverseEP,
  title={Adverse event profile of tramadol in recent clinical studies of chronic osteoarthritis pain},
  author={Paul C Langley and Anuprita D Patkar and Kimberly A Boswell and Carmela J. Benson and Jeffrey R. Schein},
  journal={Current Medical Research and Opinion},
  year={2010},
  volume={26},
  pages={239 - 251}
}
Abstract Objective: To review the safety profile of tramadol hydrochloride (tramadol) in the treatment of chronic osteoarthritis pain, with specific reference to the incidence of adverse events (AEs) reported in large clinical trials. Methods: An extensive review of published clinical trials with tramadol was conducted, using literature searches in MEDLINE and EMBASE (since 1997) and the key search terms: tramadol, immediate-release (IR), extended-release (ER), sustained-release (SR), chronic… 
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