Adverse effects profile of the herbal antidepressant St. John's wort (Hypericum perforatum L.)

  title={Adverse effects profile of the herbal antidepressant St. John's wort (Hypericum perforatum L.)},
  author={E. Ernst and J. Rand and J. Barnes and C. Stevinson},
  journal={European Journal of Clinical Pharmacology},
  • E. Ernst, J. Rand, +1 author C. Stevinson
  • Published 1998
  • Medicine
  • European Journal of Clinical Pharmacology
  • AbstractObjective: This paper provides a systematic review of adverse drug reactions (ADRs) associated with the use of extracts of the herb St. John's wort (Hypericum perforatum L.) for the treatment of mild to moderate depression. Methods: Searches of four computerized literature databases were performed for records of (ADRs). Manufacturers of hypericum products, the international drug monitoring centre of the World Health Organization (WHO) and the national drug safety monitoring bodies of… CONTINUE READING
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