Adverse effects of treatment in childhood acute lymphoblastic leukemia: general overview and implications for long-term cardiac health.

@article{Ness2011AdverseEO,
  title={Adverse effects of treatment in childhood acute lymphoblastic leukemia: general overview and implications for long-term cardiac health.},
  author={Kirsten K. Ness and Saro H. Armenian and Nina S Kadan-Lottick and James G. Gurney},
  journal={Expert review of hematology},
  year={2011},
  volume={4 2},
  pages={185-97}
}
Survival of childhood acute lymphoblastic leukemia (ALL) is one of the greatest medical success stories of the last four decades. Unfortunately, childhood ALL survivors experience medical late effects that increase their risk of morbidity and premature death, often due to heart and vascular disease. Research has helped elucidate the mechanisms and trajectory of direct damage to the heart from treatment exposure, particularly to anthracyclines, and has also contributed knowledge on the… CONTINUE READING
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