Adverse effects of three different forms of heparin therapy: thrombocytopenia, increased transaminases, and hyperkalaemia

@article{Monreal1989AdverseEO,
  title={Adverse effects of three different forms of heparin therapy: thrombocytopenia, increased transaminases, and hyperkalaemia},
  author={Manuel Monreal and E. Lafoz and Renato Salvador and Javier Roncal{\'e}s and Arturo Navarro},
  journal={European Journal of Clinical Pharmacology},
  year={1989},
  volume={37},
  pages={415-418}
}
A prospective study has been made of the incidence of changes in transaminase levels, hyperkalaemia and thrombocytopenia in three groups of patients: 89 consecutive patients with venous thrombosis receiving therapeutic heparinization, 49 patients admitted because of hip fracture and receiving prophylactic low-dose conventional heparin, and 43 patients admitted because of hip fracture and randomly allocated to receive low molecular weight heparin. Laboratory measurements were made on admission… CONTINUE READING

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A prospective study has been made of the incidence of changes in transaminase levels , hyperkalaemia and thrombocytopenia in three groups of patients : 89 consecutive patients with venous thrombosis receiving therapeutic heparinization , 49 patients admitted because of hip fracture and receiving prophylactic low - dose conventional heparin , and 43 patients admitted because of hip fracture and randomly allocated to receive low molecular weight heparin .
A prospective study has been made of the incidence of changes in transaminase levels , hyperkalaemia and thrombocytopenia in three groups of patients : 89 consecutive patients with venous thrombosis receiving therapeutic heparinization , 49 patients admitted because of hip fracture and receiving prophylactic low - dose conventional heparin , and 43 patients admitted because of hip fracture and randomly allocated to receive low molecular weight heparin .
In contrast , only one patient on low molecular weight heparin developed abnormal AlT activity .
A prospective study has been made of the incidence of changes in transaminase levels , hyperkalaemia and thrombocytopenia in three groups of patients : 89 consecutive patients with venous thrombosis receiving therapeutic heparinization , 49 patients admitted because of hip fracture and receiving prophylactic low - dose conventional heparin , and 43 patients admitted because of hip fracture and randomly allocated to receive low molecular weight heparin .
heparinContraindicated with diseaseThrombocytopenia
A prospective study has been made of the incidence of changes in transaminase levels , hyperkalaemia and thrombocytopenia in three groups of patients : 89 consecutive patients with venous thrombosis receiving therapeutic heparinization , 49 patients admitted because of hip fracture and receiving prophylactic low - dose conventional heparin , and 43 patients admitted because of hip fracture and randomly allocated to receive low molecular weight heparin .
Adverse effects of three different forms of heparin therapy : thrombocytopenia , increased transaminases , and hyperkalaemia .
Only two patients on high - dose heparin developed thrombocytopenia .
A prospective study has been made of the incidence of changes in transaminase levels , hyperkalaemia and thrombocytopenia in three groups of patients : 89 consecutive patients with venous thrombosis receiving therapeutic heparinization , 49 patients admitted because of hip fracture and receiving prophylactic low - dose conventional heparin , and 43 patients admitted because of hip fracture and randomly allocated to receive low molecular weight heparin .
A prospective study has been made of the incidence of changes in transaminase levels , hyperkalaemia and thrombocytopenia in three groups of patients : 89 consecutive patients with venous thrombosis receiving therapeutic heparinization , 49 patients admitted because of hip fracture and receiving prophylactic low - dose conventional heparin , and 43 patients admitted because of hip fracture and randomly allocated to receive low molecular weight heparin .
A prospective study has been made of the incidence of changes in transaminase levels , hyperkalaemia and thrombocytopenia in three groups of patients : 89 consecutive patients with venous thrombosis receiving therapeutic heparinization , 49 patients admitted because of hip fracture and receiving prophylactic low - dose conventional heparin , and 43 patients admitted because of hip fracture and randomly allocated to receive low molecular weight heparin .
In contrast , only one patient on low molecular weight heparin developed abnormal AlT activity .
A prospective study has been made of the incidence of changes in transaminase levels , hyperkalaemia and thrombocytopenia in three groups of patients : 89 consecutive patients with venous thrombosis receiving therapeutic heparinization , 49 patients admitted because of hip fracture and receiving prophylactic low - dose conventional heparin , and 43 patients admitted because of hip fracture and randomly allocated to receive low molecular weight heparin .
A prospective study has been made of the incidence of changes in transaminase levels , hyperkalaemia and thrombocytopenia in three groups of patients : 89 consecutive patients with venous thrombosis receiving therapeutic heparinization , 49 patients admitted because of hip fracture and receiving prophylactic low - dose conventional heparin , and 43 patients admitted because of hip fracture and randomly allocated to receive low molecular weight heparin .
A prospective study has been made of the incidence of changes in transaminase levels , hyperkalaemia and thrombocytopenia in three groups of patients : 89 consecutive patients with venous thrombosis receiving therapeutic heparinization , 49 patients admitted because of hip fracture and receiving prophylactic low - dose conventional heparin , and 43 patients admitted because of hip fracture and randomly allocated to receive low molecular weight heparin .
In contrast , only one patient on low molecular weight heparin developed abnormal AlT activity .
A prospective study has been made of the incidence of changes in transaminase levels , hyperkalaemia and thrombocytopenia in three groups of patients : 89 consecutive patients with venous thrombosis receiving therapeutic heparinization , 49 patients admitted because of hip fracture and receiving prophylactic low - dose conventional heparin , and 43 patients admitted because of hip fracture and randomly allocated to receive low molecular weight heparin .
A prospective study has been made of the incidence of changes in transaminase levels , hyperkalaemia and thrombocytopenia in three groups of patients : 89 consecutive patients with venous thrombosis receiving therapeutic heparinization , 49 patients admitted because of hip fracture and receiving prophylactic low - dose conventional heparin , and 43 patients admitted because of hip fracture and randomly allocated to receive low molecular weight heparin .
A prospective study has been made of the incidence of changes in transaminase levels , hyperkalaemia and thrombocytopenia in three groups of patients : 89 consecutive patients with venous thrombosis receiving therapeutic heparinization , 49 patients admitted because of hip fracture and receiving prophylactic low - dose conventional heparin , and 43 patients admitted because of hip fracture and randomly allocated to receive low molecular weight heparin .
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