Adverse effects of reduced-dose d-penicillamine in children with mild-to-moderate lead poisoning.

Abstract

BACKGROUND Oral chelation therapy with d-penicillamine (d-PCN) has been proven to be effective in the treatment of mild-to-moderate lead poisoning. However, d-PCN is associated with a relatively high incidence of adverse effects when given in the standard dose of 25-30 mg/kg/d. Lower doses of d-PCN may reduce the rate of adverse effects without a… (More)

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