Adverse effects of lupus anticoagulant positive blood sera on placental viability can be prevented by heparin in vitro.

Abstract

OBJECTIVE Lupus anticoagulant poses a significant risk factor for obstetric complications, whereas heparin improves live birth rates in those pregnancies. Pathophysiology of antiphospholipid antibodies on placental function involves coagulopathies and thrombosis but also dysregulated trophoblast turnover. STUDY DESIGN With the use of placental explant… (More)

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@article{Bose2004AdverseEO, title={Adverse effects of lupus anticoagulant positive blood sera on placental viability can be prevented by heparin in vitro.}, author={Patrick Bose and Simon Black and Mamed Kadyrov and Clemens Bartz and Abdul A Shlebak and Lesley Regan and Berthold Huppertz}, journal={American journal of obstetrics and gynecology}, year={2004}, volume={191 6}, pages={2125-31} }