Adverse effects and treatment satisfaction among online users of four antidepressants

  title={Adverse effects and treatment satisfaction among online users of four antidepressants},
  author={Shannon Hughes and Jeffrey Lacasse and Reid Rogers Fuller and Jennifer Spaulding-Givens},
  journal={Psychiatry Research},
Adverse Events Due to Insomnia Drugs Reported in a Regulatory Database and Online Patient Reviews: Comparative Study
It is concluded that online patient reviews of hypnotics are a valid source that can supplement traditional adverse event reporting systems and is influenced by considerations of efficacy and adverse events, while drug cost is unimportant.
Evaluation of Emotional Adverse Effects of Antidepressants
The results suggest that the score obtained from OQESA may be related not only to the emotional adverse effects of antidepressants but also to the residual symptoms of depression.
Adverse Effects of Antidepressants Reported by a Large International Cohort: Emotional Blunting, Suicidality, and Withdrawal Effects.
A cost-benefit analysis that cannot justify the extremely high prescription rates for these drugs is implied, especially in the emotional, psychological and interpersonal domains.
A Systematic Review of the Psychiatric-Adverse Effects associated with the Administration of Vilazodone
INTRODUCTION Adverse Drug Reactions (ADRs) can affect patients irrespective of age or gender, ultimately impacting morbidity and mortality (Schellack N, et al., 2018). ADRs have become a major global
The micro-to-macro realities of antidepressant taking: Users’ experiences in the context of contested science and industry promotion
The macro landscape shaping antidepressant use is marked by uncertain and contested research and vigorous pharmaceutical promotion to doctors and (in the U.S.) patients. While prior studies have
Investigating Care Dependency and Its Relation to Outcome (ICARE): Results From a Naturalistic Study of an Intensive Day Treatment Program for Depression
The results suggest that care dependency might be associated with a worse treatment outcome in depressed patients, and care dependency seems to be a dynamic construct, as it is changing over time, while the levels of care dependency seem to be independent from the received type of treatment.
Anhedonia w zaburzeniach depresyjnych
Agomelatine is an antidepressant with the best documented and proven efficacy in reducing the increased depressive anhedonia and the lowest potential to cause drug-inducedAnhedonia, which results in the enhancement of dopaminergic and noradrenergic transmission.
Antidepressant-Related Apathy: Implications for Practice
  • K. Plowden
  • Medicine, Psychology
    The Journal for Nurse Practitioners
  • 2019
Expanding the purview of wellness indicators: validating a new measure that includes attitudes, behaviors, and perspectives
ABSTRACT Objective The present study validated the DeltaQuest Wellness Measure (DQ Wellness), a new 15-item measure of wellness that spans relevant attitudes, behaviors, and perspectives. Design This
Twenty years after ‘Listening to Prozac but hearing placebo’. Do we hear placebo even louder?
It was found that persons who expect the occurrence of side effects of a pure placebo taken under the guise of an antidepressant present a higher degree of depressive symptoms than persons who do not expect the phenomenon.


Adverse reactions to antidepressants.
Most complaints listed as adverse reactions in people with depression were more common when they were medication-free rather than during their treatment with antidepressants, suggesting attention to specific adverse reactions may improve adherence to antidepressant treatment.
The psychoactive effects of antidepressants and their association with suicidality.
The effects identified are consistent with other data, and suggest that some antidepressants may induce emotional effects that are experienced as unpleasant, may impact on the symptoms of mental disorders, and may account for the suggested occurrence of increased suicidal impulses in some users.
Emotional side-effects of selective serotonin reuptake inhibitors: qualitative study.
Emotional side-effects of SSRIs are a robust phenomenon, prominent in some people's thoughts about their medication, having a demonstrable impact on their functioning and playing a role in their decision-making about antidepressant adherence.
Adverse event assessment methods in published trials of psychotropic drugs: Poor reporting and neglect of emerging safety concerns.
To investigate whether AE assessment has changed over time for three psychotropic drugs with turbulent histories of safety concerns since their U.S. approval, verbatim AE assessment and numbers of words describing efficacy and safety assessment were extracted.
Comparative Benefits and Harms of Second-Generation Antidepressants for Treating Major Depressive Disorder
Current evidence does not warrant recommending a particular second-generation antidepressant on the basis of differences in efficacy, but differences in onset of action and adverse events may be considered when choosing a medication.
Reasons for Quitting Serotonin Reuptake Inhibitor Therapy: Paradoxical Psychological Side Effects and Patient Satisfaction
Psychological side effects might well be included in measures and discussions of side effects, even though they present no known physical danger to the patient.
Can Online Consumers Contribute to Drug Knowledge? A Mixed-Methods Comparison of Consumer-Generated and Professionally Controlled Psychotropic Medication Information on the Internet
The most frequently reported effects of escitalopram and quetiapine in online consumer reviews were described to compare them with effects described in professionally controlled commercial health websites, and to gauge the usability of online consumer medication reviews.
What Is Really Known About Psychological Alterations Produced by Psychiatric Drugs?
The article considers the possibility that nominal “therapeu tic” drug effects may only be part of a larger, inadequately discerned picture of drug-induced psychological toxicity, and the RCT format needs to be modified so that the investigation of treatment efficacy is only part of an systematic effort to ascertain the full range of psychological alterations brought about by the drug.
A review of current evidence for vilazodone in major depressive disorder
Vilazodone is a newer antidepressant possessing different action mechanisms compared to currently available antidepressants but whether it has superiority to other class of antidepressants in terms of efficacy and safety should still warrant further evaluation through more well-controlled and direct comparison clinical trials.