Corpus ID: 28041501

Adverse drug reactions to a cephalosporins in hospitalized patients with a history of penicillin allergy.

  title={Adverse drug reactions to a cephalosporins in hospitalized patients with a history of penicillin allergy.},
  author={Luz Fonacier and R. Hirschberg and Steve Gerson},
  journal={Allergy and asthma proceedings},
  volume={26 2},
Estimates on the cross-reactivity between cephalosporin and penicillin range from 1 to 16%. Patients with a history of penicillin allergy usually receive less optimal and more costly alternatives even if cephalosporins are a more viable alternative. One hundred eighty-six patients admitted to Winthrop University Hospital in a 7.5-month period, who reported penicillin allergy and received cephalosporin, were sent surveys. Eighty-three patients completed the survey and their charts were reviewed… Expand
The use of cephalosporins in penicillin-allergic patients: a literature review.
Overall cross reactivity between penicillins and cephalosporins is lower than previously reported, though there is a strong association between amoxicillin and ampicillin with first- and second-generation cep Halosporin that share a similar R1 side chain. Expand
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A 10% cross-reactivity rate is commonly cited between penicillins and cephalosporins. However, this figure originated from studies in the 1960s and 1970s which included first-generationExpand
Use of cephalosporins in patients with immediate penicillin hypersensitivity: cross-reactivity revisited.
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  • Medicine
  • Hong Kong medical journal = Xianggang yi xue za zhi
  • 2014
Drug provocation test by experienced personnel remains the best way to exclude or confirm the diagnosis of drug hypersensitivity and to find a safe alternative for future use of cephalosporins. Expand
Penicillin-allergic patients : Use of cephalosporins , carbapenems , and monobactams
Antigenic components of penicillins — In order to understand the possible cross reactivity among penicillins, cephalosporins, carbapenems and monobactams, it is helpful to review the potentialExpand
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Clinicians should consider the low likelihood of true cephalosporin allergy when clinically indicated and be cognizant of R1 side chain similarities when prescribing alternate β-lactams in allergic individuals or when new cep Khalosporins are brought to market. Expand
Penicillin and Beta-Lactam Hypersensitivity.
Skin testing remains the optimal method for evaluation of possible IgE-mediated penicillin allergy and is recommended by professional societies, as the harms for alternative antibiotics include antimicrobial resistance, prolonged hospitalizations, readmissions, and increased costs. Expand
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  • R. Mirakian, S. Leech, +7 authors S. Nasser
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  • Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
  • 2015
A guideline for the management of immediate and non‐immediate allergic reactions to penicillins and other beta‐lactams is intended for UK specialists in both adult and paediatric allergy and for other clinicians practising allergy in secondary and tertiary care. Expand
Assessment of the Frequency of Dual Allergy to Penicillins and Cefazolin: A Systematic Review and Meta-analysis.
These findings suggest that most patients with a penicillin allergy history may safely receive cefazolin, and the exception is patients with confirmed peniillin allergy in whom additional care is warranted. Expand
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Pattern of adverse drug reactions to antibiotics commonly prescribed in department of medicine and pediatrics in a tertiary care teaching hospital, Ghaziabad -
It was revealed that antibiotics comprise the major volume of the drug family and inpatient prescriptions and thus are the most irrationally prescribed and therefore implementation of antibiotic guideline policy for the hospitals and strict adherence to it should be ensured to promote their rational and safe use. Expand